- [[#people with weird health issues|people with weird health issues]] - [[#OCD|OCD]] - [[#Very interesting!!!!|Very interesting!!!!]] - [[#Very interesting!!!!#Extra Relevant|Extra Relevant]] - studies talking about setups - [[#On Addiction|On Addiction]] - [[#Intranasal Application|Intranasal Application]] - [[#Very interesting!!!!#investigate more!|investigate more!]] - [[#Very interesting!!!!#lol what|lol what]] - [[#About therapeutics|About therapeutics]] - stress - [[#How it works?|How it works?]] - [[#not that relevant|not that relevant]] - [[#How it works?#Liposome Stuff|Liposome Stuff]] - [[#xenon light therapy|xenon light therapy]] - [[#xenon light therapy#Weird ROAs|Weird ROAs]] - [[#Not that related but interesting|Not that related but interesting]] - [[#Not that related but interesting#Anesthesia related|Anesthesia related]] - [[#Not that related but interesting#Has lists of papers that are probably not that relevant|Has lists of papers that are probably not that relevant]] - [[#Liposome Stuff#Probably Very Irrelevant|Probably Very Irrelevant]] - [[#Has lists of papers that are probably not that relevant#Rats|Rats]] - [[#Has lists of papers that are probably not that relevant#Find source|Find source]] - [[#Not that related but interesting#Papers for Circuit Design|Papers for Circuit Design]] - [[#Find source#Weird sources|Weird sources]] - xenon assisted psychotherapy - fybromyalgia Questions: - xenon - scott alexander question - Does the effect last? - gather more sources - anxiety - done - depression - done - ptsd - done - autism - done - schizophrenia - almost nothing afaict - bipolar - basically nothing - addiction - on laptop... - ocd - almost nothing - stress - not much - ROA - transdermal delivery - some, rather arcane and hard to understand - xenon infusion iv and intranasal - rat papers? - japanese/chinese/russian lang - judgement criteria (expand) - does the paper have data on how the patients feel for duration of study - does it have data on how they feel after the study Chinese search - We searched for Chinese language publications with the search term “氙 [xenon] and (神經 [neuro] or 認知 [cognitive])” in Wanfang [萬方數據 Russian search - We searched for Russian language publications with the search term “кceнoн” in elibrary.ru and “кceнoн [xenon] AND (нeйpoпpoтeкции [neuroprotection] OR нeвpoлoгичecкий [neurologic] OR пoзнaвaтeльный [cognitive])” in Google Scholar, as we expected a considerable number of Russian studies.[41](https://link.springer.com/article/10.1007/s12630-018-1163-6#ref-CR41 "Maze M, Pirracchio R. Will xenon be a valuable addition in perioperative and critical care settings? Anesth Analg 2016; 122: 593-6.") Japanese search - I can probably try this Bountied rationality post: I'm looking for studies on using xenon for therapeutic purposes and will pay 8$ check if 8 or 7 per study you find that fit my criteria that I haven't already found. I'm looking for studies on Xenon used therapeutically for treating any of: - depression - anxiety/panic attacks - trauma/PTSD - workplace stress (like this paper on xenon for fighter pilots) - OCD - addiction - autism/schizophrenia/bipolar - reducing trauma following major surgeries (e.g. this one about breast removal) and also: - must not be an animal study Some tips: - I've searched mainly on Google scholar for these. If you check other sites, languages Chinese Russian spanish - You can check what papers I and others have found at: xenon.raj.quest To submit a paper, use this form: paper.raj.quest 09:49 maybe these two are related, share author(s) [Correction of the functional state of deck aviation pilots by the course of inhalation of therapeutic doses of xenon during long march](https://europepmc.org/article/med/21970037) [Sci-Hub | Correction of the functional state of aircraft-carrier aviation pilots by a course of inhalation of therapeutic doses of xenon during a long sea campaign | 10.1134/S0362119713070050 (gupiaoq.com)](https://sci-hub.gupiaoq.com/10.1134/S0362119713070050) [DEVELOPMENT OF POSTCASTRATION SYNDROME AND CORRECTIVE EFFECT OF XENON IN EXPONENTIAL DOSE REGIMEN IN YOUNG PATIENTS WITH GYNECOLOGICAL CANCERS](https://www.cancersp.com/jour/article/viewFile/69/32.pdf) interesting about mechanism of action? [Homeostatic and endocrine responses as the basis for systemic therapy with medical gases ozone, xenon and molecular hydrogen](https://journals.lww.com/mgar/fulltext/2021/11040/Homeostatic_and_endocrine_responses_as_the_basis.8.aspx) ##### people with weird health issues - [abstract on medical xenon for people with somatoform disorders](https://hrcak.srce.hr/en/file/383868) ##### OCD ##### Very interesting!!!! - [New treatments for ocd (thewrightinitiative.com)](https://thewrightinitiative.com/misc/new-treatments-for-ocd.html) - talks about muscle tension causes of ocd or something. send to vasocomp guy and andres [Study Details | Trial of Low-Dose Xenon For The Treatment Of Obsessive-Compulsive Disorder | ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT02098148) withdrawn study...some other studies have happened at mclean i think ###### Extra Relevant talks about exactly what i want re anxiety: [Full article: Experimental Drugs for Panic Disorder: An Updated Systematic Review (tandfonline.com)](https://www.tandfonline.com/doi/full/10.2147/JEP.S261403#d1e411) #### On Addiction - [Xenontherapy of withdrawal syndrom among the patients with opioid dependence | European Psychiatry | Cambridge Core](https://www.cambridge.org/core/journals/european-psychiatry/article/xenontherapy-of-withdrawal-syndrom-among-the-patients-with-opioid-dependence/17DED148CFBC6EEAD25BA5E96DC2DC8A) dobrovosky - [Effects of inhaled low-concentration xenon gas on naltrexone-precipitated withdrawal symptoms in morphine-dependent mice - ScienceDirect](https://www.sciencedirect.com/science/article/pii/S037687162301205X?casa_token=v8bJqcDD8msAAAAA:9p0tAi1vGMnnKMBvCZVJETbXmyhNwh7CxAczP3c-jR97UnU1Nx57d6WSIwswGQ9JyjUvLwE1og) mouse study - [CLINICAL APPLICATION OF XENON THERAPY IN PATIENTS DUE OPIOID WITHDRAWAL SYNDROME](https://hrcak.srce.hr/file/382524) [THE POSSIBILITIES OF XENON APPLICATION IN COMPLEX THERAPY OF PSYCHO-PATHOLOGIC DISORDERS IN PATIENTS OF NARCOLOGIC PROFILE](https://medjrf.com/0869-2106/article/view/38066) - [*PDF Source*]([THE POSSIBILITIES OF XENON APPLICATION IN COMPLEX THERAPY OF PSYCHO-PATHOLOGIC DISORDERS IN PATIENTS OF NARCOLOGIC PROFILE - PDF (Russian) - Tzigankov - Russian Medicine (medjrf.com)](https://medjrf.com/0869-2106/article/view/38066/25349)) - pretty promising ###### investigate more! [Specific xenon-based gas mixtures used for stress correction therapy in patients exposed to lethal force scenarios - Ushakov - Medical-biological and social-psychological issues of safety in emergency situations (rcsi.science)](https://journals.rcsi.science/1995-4441/article/view/259833) [Dnb-30_OPATIJA_S1_P06.pdf (srce.hr)](https://hrcak.srce.hr/en/file/382523) ###### lol what [Yoga breathing in xenon therapy](https://yoga-sci.eu/wp-content/uploads/2014/06/7-yudin-e.pdf) #### About therapeutics [Practicing subnarcotic xenon dose inhalation in spa treatment of posttraumatic stress-induced disorders](https://drive.google.com/file/d/1BymHhmbb85WbFkX6OwTFQbc6Nz9pvGth/view?usp=sharing) [Adaptation Biology and Medicine: Volume 8: - Google Books](https://books.google.com/books?hl=en&lr=&id=Ieu-DwAAQBAJ&oi=fnd&pg=PA261&dq=xenon+therapy+depression&ots=KomP621X-E&sig=F14iAka0-mkRpcJZfyOxu2JK78E#v=onepage&q=xenon%20therapy%20depression&f=false) need to read/think more, try to get the pdf #### Pain [Effect of xenon-oxygen inhalations on functional status of cardiovascular system in oncological patients suffering chronic pain syndrome | Potievskaya | Research and Practical Medicine Journal (rpmj.ru)](https://www.rpmj.ru/rpmj/article/view/785?locale=en_US) Pain severity was significantly alleviated in the main group from 50 [40; 60] to 40 [25; 50]%; p < 0,05. Satisfaction of the patients in xenon group was 71 % vs 11 % in control group; p = 0,0001. #### Bipolar/Depression [Rally | Xenon Therapy for Major Depressive Disorder and Bipolar Disorder for Currently Depressed Patients (massgeneralbrigham.org)](https://rally.massgeneralbrigham.org/study/xenon) #### PTSD / Trauma [Xenon Inhalation for Treatment of Posttraumatic Stress Disorder (veeva.com)](https://ctv.veeva.com/study/xenon-inhalation-for-treatment-of-posttraumatic-stress-disorder) [THE ANTISTRESS EFFECT OF XENON IN SUBNARCOTIC CONCENTRATIONS IN CHILDREN WITH SEVERE INJURIES - Bagaev - Russian Journal of Pediatric Surgery (jps-nmp.ru)](https://jps-nmp.ru/jour/article/view/237) ##### some other therapeutics [The neuroprotective effect and possible therapeutic application of xenon in neurological diseases - PubMed (nih.gov)](https://pubmed.ncbi.nlm.nih.gov/34716615/) add link to file from sciAlt [Prospects of Xenon Application in Functional Recovery and Rehabilitation of Patients Working in Extreme Occupational Environments]([Prospects of Xenon Application in Functional Recovery and Rehabilitation of Patients Working in Extreme Occupational Environments | Request PDF (researchgate.net)](https://www.researchgate.net/publication/369027227_Prospects_of_Xenon_Application_in_Functional_Recovery_and_Rehabilitation_of_Patients_Working_in_Extreme_Occupational_Environments)) add file. in russian #### How it works? [Journal of Neuroscience Research | JNR Neuroscience Journal | Wiley Online Library](https://onlinelibrary.wiley.com/doi/abs/10.1002/jnr.24958?casa_token=RA2tleUSDfoAAAAA%3ApeE6AlTXTaak9wusWWtG9hgjO8xWjWCR4y1IyEtzJwmDBrkgx3WUf7h-DoxRmZ0YibTnOsfjo57_kOU) [Neuroprotective and neurorestorative potential of xenon | Cell Death & Disease (nature.com)](https://www.nature.com/articles/cddis201686) [The neuroprotective effect and possible therapeutic application of xenon in neurological diseases](https://onlinelibrary.wiley.com/doi/abs/10.1002/jnr.24958?casa_token=2axWlljkC4wAAAAA%3A0O5USwOGeVXzk_wbNwMLLNhn5goPTT0mIAoWSiGzDy_-OnsQLR7mdLkKw1ymFmKNWg6MNwDHF5v3uyE) [OZONE AND XENON STRESS CORRECTION](https://core.ac.uk/download/pdf/158643827.pdf) ### not that relevant [Disorders of the cardiovascular system performance in the early post-castration period in patients with locally advanced cervical cancer and their correction with the low-dose xenon therapy - ProQuest](https://www.proquest.com/docview/2405906943?pq-origsite=gscholar&fromopenview=true&sourcetype=Scholarly%20Journals) [Effects of xenon anesthesia on postoperative neurocognitive disorders: a systematic review and meta-analysis | BMC Anesthesiology (springer.com)](https://link.springer.com/article/10.1186/s12871-023-02316-5) [[Non-hormonal correction of menopausal syndrome: potential of xenon therapy]. - Abstract - Europe PMC](https://europepmc.org/article/med/34719907) [Nitrous Oxide and Xenon Prevent Amphetamine-Induced Carrier-Mediated Dopamine Release in a Memantine-Like Fashion and Protect Against Behavioral Sensitization - ScienceDirect](https://www.sciencedirect.com/science/article/pii/S0006322305012722?casa_token=Ax5_ILswXF8AAAAA:1bWghCYkKsqJjd2sK9h8T2q_VbCO4D4JttpLtYOJ-kBH9rAQzS2494HXf129m4eJetKadLSSZA) ##### Liposome Stuff [Intravenous infusion of xenon-containing liposomes generates rapid antidepressant-like effects - ScienceDirect](https://www.sciencedirect.com/science/article/pii/S0278584617310400?casa_token=1bTchDrItgcAAAAA:8Y7RngCdBMKCgbFnj_vyueHzy6grHqsGe9FS3W8wdlUDtS2kDGK7s6nUoW_2cCkOz-UZBrqdhg) [Xenon incorporated in a lipid emulsion inhibits NMDA receptor channels - Weigt - 2003 - Acta Anaesthesiologica Scandinavica - Wiley Online Library](https://onlinelibrary.wiley.com/doi/full/10.1034/j.1399-6576.2003.00221.x) apparently you can dissolve xenon in lipofundin ### xenon light therapy [Change of Tinnitus with Xenon Phototherapy of the Stellate Ganglion | Photomedicine and Laser Surgery (liebertpub.com)](https://www.liebertpub.com/doi/abs/10.1089/pho.2017.4431) [Intranasal irradiation with the xenon chloride ultraviolet B laser improves allergic rhinitis - ScienceDirect](https://www.sciencedirect.com/science/article/abs/pii/S1011134404000624) liposomes [Intravenous infusion of xenon-containing liposomes generates rapid antidepressant-like effects - ScienceDirect](https://www.sciencedirect.com/science/article/pii/S0278584617310400?casa_token=1bTchDrItgcAAAAA:8Y7RngCdBMKCgbFnj_vyueHzy6grHqsGe9FS3W8wdlUDtS2kDGK7s6nUoW_2cCkOz-UZBrqdhg) [Antidepressant and antioxidant effects of transcranial irradiation with 830-nm low-power laser in an animal model of depression | Lasers in Medical Science (springer.com)](https://link.springer.com/article/10.1007/s10103-021-03410-1) rat liposome stuff #### Weird ROAs ##### Transdermal [Transdermal diffusion of xenon from lipophilic solution of capric triglyceride and from water | Auctores (auctoresonline.org)](https://auctoresonline.org/article/transdermal-diffusion-of-xenon-from-lipophilic-solution-of-capric-triglyceride-and-from-water) [Transdermal delivery of xenon from lipophilic solution and water (psu.edu)](https://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=7c93d9e047f11d3d2a524e3475241de5a441a2d3) [Transdermal diffusion of xenon in vitro using diffusion cells | AIP Conference Proceedings | AIP Publishing](https://pubs.aip.org/aip/acp/article-abstract/1688/1/030012/805493/Transdermal-diffusion-of-xenon-in-vitro-using) doesn't seem that useful [The Development of Technology for Topical Application of Xenon as Part of an External Agent and Its Effect on Rat Skin Wound Healing](https://www.matec-conferences.org/articles/matecconf/abs/2016/42/matecconf_imet2016_01004/matecconf_imet2016_01004.html) very weird! Very interesting! talks a bit about how they made the cream/ingredients [Therapeutic gas delivery via microbubbles and liposomes](https://drive.google.com/file/d/1AFO72-d3m-FJXT8SmQoHiG9h-dxHF6mb/view?usp=drive_link) [In vitro-evaluation of lipid emulsions as vehicles for the administration of xenon: Interaction with NMDA receptors | Acta Neurobiologiae Experimentalis](https://ane.pl/index.php/ane/article/view/1746) follow-up possibly to 2003 paper Xenon incorporated in a lipid emulsion inhibits NMDA receptor channels ##### Water [Manufacturing the Technology of Xenon-Containing Drinking Water and its Influence on Some Psychophysiological Characteristics of Man](https://www.matec-conferences.org/articles/matecconf/pdf/2016/42/matecconf_imet2016_01058.pdf) #### Intranasal Application [[2111.10231] The method of inhalation therapy with micro-doses of mixtures noble gases with oxygen (arxiv.org)](https://arxiv.org/abs/2111.10231) promising [Intranasal Application of Xenon Reduces Opioid Requirement and Postoperative Pain in Patients Undergoing Major Abdominal Surgery | Anesthesiology | American Society of Anesthesiologists (asahq.org)](https://pubs.asahq.org/anesthesiology/article/115/2/398/11096/Intranasal-Application-of-Xenon-Reduces-Opioid) [Intranasal application of xenon: describing the pharmacokinetics in experimental animals and the increased pain tolerance within a placebo-controlled experimental human study | BJA: British Journal of Anaesthesia | Oxford Academic (oup.com)](https://academic.oup.com/bja/article/104/3/351/229949) [Intranasal Use Criticism and Reply](https://drive.google.com/file/d/1P89fSed8UuvTWlVNH1oq5Bu0kfHtPwok/view?usp=drive_link) ### Not that related but interesting [Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908650/) [Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders - ScienceDirect](https://www.sciencedirect.com/science/article/pii/S0163725819301512) [Sci-Hub | Changes in Frontal Lobe Activity With Cognitive Therapy for Spider Phobia | 10.1207/s15324826an1301_5 (gupiaoq.com)](https://sci-hub.gupiaoq.com/https%3A//doi.org/10.1207/s15324826an1301_5) only mentions xenon inhalation once? really not clear if they actually use it #### Anesthesia related [Neuroprotection by Nitrous Oxide and Xenon and Its Relation to Minimum Alveolar Concentration | Anesthesiology | American Society of Anesthesiologists (asahq.org)](https://pubs.asahq.org/anesthesiology/article/101/1/260/8526/Neuroprotection-by-Nitrous-Oxide-and-Xenon-and-Its) [The-Effectiveness-of-Xenon-Sedation-in-Laser-Refractive-Interventions-on-the-Cornea.pdf (researchgate.net)](https://www.researchgate.net/profile/Av-Romanov/publication/378697220_The_Effectiveness_of_Xenon_Sedation_in_Laser_Refractive_Interventions_on_the_Cornea/links/65e58a09adf2362b636a7d0c/The-Effectiveness-of-Xenon-Sedation-in-Laser-Refractive-Interventions-on-the-Cornea.pdf) [Xenon Blocks the Induction of Synaptic Long-Term Potentiation in Pain Pathways in the Rat Spinal Cord _In Vivo](https://journals.lww.com/anesthesia-analgesia/fulltext/2007/01000/xenon_blocks_the_induction_of_synaptic_long_term.22.aspx?casa_token=aMXUQIsh3FwAAAAA:3SEzOcnq46tTorp1RGcSLk-fFn_FTXRE-XGpXNPP1XRm2y6KeyyQK2P5tyA3LePDQg7jj6-Vel19lggJEkzGkRs&casa_token=spyhKew48AEAAAAA:UN1uR4zVtp1ErdDFapaqkZ2YggcezNzlRkzZn2vXcaQnCMC4MkEV895gCxGyz7v42M9dstdbYdjSGR5PLaTIPpI) #### Has lists of papers that are probably not that relevant [Neurologic and cognitive outcomes associated with the clinical use of xenon: a systematic review and meta-analysis of randomized-controlled trials | Canadian Journal of Anesthesia/Journal canadien d'anesthésie (springer.com)](https://link.springer.com/article/10.1007/s12630-018-1163-6) This study conformed to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) statement.[40](https://link.springer.com/article/10.1007/s12630-018-1163-6#ref-CR40 "Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 2009; 62: e1-34.") We searched for RCTs that compared xenon with any type of control treatment for influence on neurologic or cognitive outcomes of clinical relevance including radiologic or biochemical effects. We used the search term “xenon AND (neuroprotect* OR neurocognit* OR cognit*)” in PubMed, CENTRAL, EMBASE, and CINAHL. We searched for Russian language publications with the search term “кceнoн” in elibrary.ru and “кceнoн [xenon] AND (нeйpoпpoтeкции [neuroprotection] OR нeвpoлoгичecкий [neurologic] OR пoзнaвaтeльный [cognitive])” in Google Scholar, as we expected a considerable number of Russian studies.[41](https://link.springer.com/article/10.1007/s12630-018-1163-6#ref-CR41 "Maze M, Pirracchio R. Will xenon be a valuable addition in perioperative and critical care settings? Anesth Analg 2016; 122: 593-6.") We searched for Chinese language publications with the search term “氙 [xenon] and (神經 [neuro] or 認知 [cognitive])” in Wanfang [萬方數據]. We did not impose restrictions on the year of publication or language. We only included human studies and excluded all non-RCTs. The latest search was done in February 2018. The two co-first authors (L.L. and E.L.) independently searched and assessed the English and Chinese literature for eligibility. The first and third authors (L.L. and C.C.) independently searched for the papers written in Russian. Conference abstracts published prior to 2016 were excluded. ##### Breast Cancer/Castration Related [Integral effects of xenon: Inhibition of postovariectomy syndrome development in young women with cervical and breast cancers. | Journal of Clinical Oncology (ascopubs.org)](https://ascopubs.org/doi/abs/10.1200/JCO.2022.40.16_suppl.e17515) ###### Probably Very Irrelevant - [Effect of xenon and argon inhalation on erythropoiesis and steroidogenesis: A systematic review: Heliyon (cell.com)](https://www.cell.com/heliyon/fulltext/S2405-8440(23)03044-X) xenon for doping - [STUDY OF THE ADAPTIVE PROPERTIES OF XENON IN COMPLEX THERAPY OF PATIENTS WITH PNEUMONIA](http://ran-nauka.ru/wp-content/uploads/2023/11/Practice-Oriented-Science-October-28-Part-1.pdf#page=114) xenon - [Study Details | RELIEF OF PSYCHOEMOTIONAL STRESS USING XENON SEDATION | ClinicalTrials.gov](https://clinicaltrials.gov/study/NCT06080100) xenon for people getting eye surgery ##### Rats https://link.springer.com/article/10.1186/s12967-019-02161-6 xenon for rat autism lol [Xenon Preconditioning: The Role of Prosurvival Signaling, Mitochondrial Permeability Transition and Bioenergetics in Rats](https://journals.lww.com/anesthesia-analgesia/fulltext/2009/03000/xenon_preconditioning__the_role_of_prosurvival.30.aspx?casa_token=BuapLGDQxWIAAAAA:fLK5F6yTyCpy2LjFFmyEOANmlJTEJRfu5xbrCCmBhDAjPzW8jMYPuyMZfcWLy4MNhWYReg5SBoBMzUD64-Kd8G0&casa_token=9BrCOWusPv0AAAAA:RgQfbT3WOsh1fErTEfO6tEo45s2uFNT6VCydyexN_VV3ddYHL82g75NOYKxupstL-QRUAFVPlCFI0L83qqV7_G0) [Intravenous infusion of xenon-containing liposomes generates rapid antidepressant-like effects - ScienceDirect](https://www.sciencedirect.com/science/article/pii/S0278584617310400?casa_token=IhHTPFoT9ZwAAAAA:QR3X8TscxGnBbEnOZTqpH_ulRcWCler2D_U2QxhO54_upJmYyVP3DWRfVqRYZ4eA0Me8X26NGQ) xenon liposome rat stuff [Xenon Impairs Reconsolidation of Fear Memories in a Rat Model of Post-Traumatic Stress Disorder (PTSD) | PLOS ONE](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0106189) rat ptsd model [ALLEVIATION OF NEUROLOGICAL AND COGNITIVE IMPAIRMENTS IN RAT MODEL OF ISCHEMIC STROKE BY 0.5 MAC XENON EXPOSURE](https://vestnik.rsmu.press/files/issues/vestnik.rsmu.press/2022/3/2022-3-1015_en.pdf) [Adaptation Effect of Repeated Xenon Application | Stryapko | General Reanimatology](https://www.reanimatology.com/rmt/article/view/1340?locale=en_US) probably not relevant, about seeing if you can make high oxygen mixtures less toxic for rats [Antistress and adaptive effects of xenon in Wistar rats](https://journals.lww.com/ejanaesthesiology/fulltext/2014/06001/antistress_and_adaptive_effects_of_xenon_in_wistar.449.aspx) [NeuroReport (lww.com)](https://journals.lww.com/neuroreport/fulltext/2020/03020/xenon_produces_rapid_antidepressant__and.3.aspx?casa_token=PIB09mOi2fgAAAAA:EovPyHWsKDv5mcBh54lwc3WOaUZsaKkuTA8sS_uiHt8nzzo7f7WaHFieEMh7zoCkPMCaUYxywNPzR9eXZMnqcCE) ##### Find source [Current Inhalation Equipment for Analgesia with the Inert Gas Xenon (researchgate.net)](https://www.researchgate.net/publication/359047964_Current_Inhalation_Equipment_for_Analgesia_with_the_Inert_Gas_Xenon) [Successful Experience of Xenon Application in the Complex of Intensive Care for Alcohol Use Disorders | EMERGENCY MEDICINE (zaslavsky.com.ua)](https://emergency.zaslavsky.com.ua/index.php/journal/article/view/358) (seems very promising) [THE POSSIBILITIES OF XENON APPLICATION IN COMPLEX THERAPY OF PSYCHO-PATHOLOGIC DISORDERS IN PATIENTS OF NARCOLOGIC PROFILE - Tzigankov - Russian Medicine (medjrf.com)](https://medjrf.com/0869-2106/article/view/38066) #### Papers for Circuit Design [The feasibility of using a portable xenon delivery device to permit earlier xenon ventilation with therapeutic cooling of neonates during ambulance retrieval - PubMed (nih.gov)](https://pubmed.ncbi.nlm.nih.gov/25794112/) - interesting because one of the authors apparently has a company that they got the portable gas thing from? inspiration healthcare ltd ###### Weird sources [Xenon therapy. An effective and delicate method of treating anxiety and depressive disorders and pain. / Article on the website of the Volyn hospital from July 20, 2021 (volynka.ru)](https://volynka.ru/Articles/Text/2620) they have a telegram https://t.me/volynka_vestnik questions: - check the cited by for all the interesting ones - why denitrogenization (pure oxygen for 5m) beforehand? - is intranasal more efficient? what happens if you IV it? - how big addiction effect - how big depression/anxiety effect